S11 Beta cell identity : Beta cell heterogeneity and dedifferentiation |
13:20~15:00 / Friday 12 October Emerald hall B Chairman: Kwang-Won Kim, Yutaka Seino |
Overview |
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Organizers: Shin Ae Kang, Hail Kim This islet biology session is entitled 'beta cell identity'. Beta cell death has been thought as the major mechanism for beta cell failure. However, recent studies indicate that beta cell dedifferentiation can result in the loss of functional beta cell mass and thereby can alter glucose homeostasis. Beta cell dedifferentiation begins with the loss of mature beta cell identity. In this session, speakers will discuss how does beta cell lose its mature identity and dedifferentiation progress. This session will broaden out understanding about the mature beta cell identity. |
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S11-1 Regulating beta cell identity | |
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S11-2 Single RNA-seq for beta cell differentiation and heteogeneity | |
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S11-3 Epigenetic control of mature -cell identity by PRMT1 dependent H4R3me2a | |
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S11-4 Non-islet cell deserves more attention; how non-islet cells help and support beta cells |
S12 Skeletal muscle energy metabolism : Skeletal muscle energy metabolism |
16:20~18:00 / Friday 12 October Emerald hall A Chairman: Joong Yeol Park, Zoltan P. Arany |
Overview |
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Organizers: Hye Soon Kim, Dae Ho Lee This translational session entitled 'skeletal muscle energy metabolism' was organized to provide pathophysiologic and therapeutic implications of diabetes and insulin resistant conditions to both physicians and basic researchers. Focusing on skeletal muscle among insulin-sensitive tissues, four excellent speakers will present and discuss about exercise type-dependent physiology, muscle thermogenesis and energy metabolism, glucose metabolism based on human clamp study, and skeletal muscle hypertrophy as a therapeutic strategy. This session will be very helpful for in-depth understating of skeletal muscle energy metabolism in both physiologic and therapeutic aspects. |
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S12-1
Regulation of skeletal muscle mitochondrial biogenesis and functions
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S12-2
Effect of hypothalamic leptin resistance on energy metabolism in skeletal muscle
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S12-3 Skeletal muscle as a therapeutic target for diabetes | |
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S12-4
Advances in understanding skeletal muscle insulin sensitivity across the lifespan
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