S5 Obesity, browning and whitening : Adipocyte lipotoxicity “friend or foe? |
09:00~10:40 / Friday 12 October Emerald hall A Chairman: Ki-Up Lee, Barbara B. Kahn |
Overview |
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Organizer: Eun Hee Koh This session entitled with 'obesity, browning and whitening' is basic session. Metabolically active brown adipose tissue playing an important role in metabolic control and body weight regulation exists in humans. Recently, many studies demonstrate that subcutaneous white adipose tissue can metabolize stored energy in brown-like ("beige" or "browing") adipocytes to contribute to overall energy expenditure. In this session, a new molecular mechanism and pathophysiology of white-to-brown adipocytes in the obesity development, will be presented and discussed. This session will present a new therapeutic strategy for managing obesity and obesity-related metabolic diseases. |
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S5-1 The dark side of PGC-1: from dark skin to dark fat | |
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S5-2
Crosstalk between adipokines and hepatokines in the maintenance of metabolic homeostasis and cardiovascular health
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S5-3 Mitophagy is necessary for the maintenance of brown fat function. | |
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S5-4 Novel roles of lipid droplet binding proteins in fat tissue |
S10 NAFLD and diabetes : Organ crosstalk in obesity and NAFLD |
13:20~15:20 / Friday 12 October Emerald hall A Chairman: Hong Kyu Lee, Sung Hee Ihm |
Overview |
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Organizers: Yong Ho Lee, Keun-Gyu Park This session entitled with 'NAFLD and diabetes' is basic and translational session and designed to provide a place for basic researchers and clinicians to understand the novel pathophysiology and potential therapeutic targets for obesity and NAFLD. In this session, various mechanisms including gut-liver or muscle-liver axis, immunology and hepatic FXR/SHP pathways will be presented and discussed by outstanding international speakers. It will also cover the repertoire of inter-organ communications and aging that have an influence on metabolic diseases. |
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S10-2 Bile acid signaling in the gut: novel therapeutic strategy for type I and II diabetes | |
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S10-3
Gα13 ablation reprograms myofibers to oxidative phenotype and enhances whole-body metabolism
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S10-4 Hepatic FXR/SHP axis modulates systemic glucose and fatty acid homeostasis in aged mice |